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An increased risk of developing diabetes with EGRIFTA (HbA1c level 6.5%) relative to placebo was observed [intent-to-treat hazard odds ratio of 3.3 (CI 1.4, 9.6)]

conservative dosing protocols are strongly recommended [2]

At the end of the preovulatory phase, the oocyte insists on meiosis and becomes a secondary oocyte, which is blocked in metaphase 2

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