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That extrapolation is reasonable and standard, but it is an extrapolation, not a Retatrutide-specific regulatory finding

However, people with low energy or less mobility may benefit more from larger MIC b12 doses

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In a head-to-head study of the two agents sponsored by Eli Lilly, makers of tirzepatide, found a 20.2% weight loss with tirzepatide compared to a 13.7% weight loss with semaglutide