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J Gerontol A Biol Sci Med Sci, 2008, 63 (10), 10271033

Some of the most common side effects (but not extremely frequent) are: anorexia weight loss dizziness fatigue or drowsiness difficulty with concentration and psychomotor slowing speech difficulty nervousness tingling or prickling sensations abnormal vision fever Additional side effects include: difficulty with memory changes in taste diarrhea numbness nausea abdominal pain upper respiratory tract infection hair loss changes in mood/suicidal thoughts These symptoms may subside after the body adjusts to the medication

Postnatal Care: After birth, babies affected by HDN may require treatments (such as phototherapy to manage jaundice), additional blood transfusions, and close monitoring of bilirubin levels to prevent kernicterus

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But for some people, the side effect profile makes it unsustainable