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Patients tapering should start the resistance program before the taper begins, not after, so the metabolic protection is in place before appetite rebounds

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This work now shows a direct line from biochemical and biophysical understanding of protein interactions to an inhibitor, says Kritzer, who was not involved in the research

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To assess the utility of the model in a real world setting, we applied the model to a set of EHR data not used during model construction, and predicted efficacy at 6 months, assuming that the drug type and final dose was unknown at time point zero