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12, 13, 14 Together, the pathological features of T2Dnotably elevated serum concentrations of inflammatory cytokines, glucose, insulin and free insulin-like growth factor-1 (IGF-1)provide a pro-tumorigenic environment that may account for the increased risk of diabetic and obese patients for the development of cancer at various sites 11 as well as the worse prognosis of patients with cancer that display one or more of these abnormalities
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Following block in 5% milk or BSA, membranes were incubated with an appropriate primary antibody from Cell Signaling (Danvers, MA) against pAkt Ser473 (1:1000
Front Microbiol
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