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in this scenario, Nrf2 redirects glucose and glutamine into anabolic pathways to support aggressive proliferation (85)

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Glutathione and Inflammation Cytokines, such as TNF-, IL-1, and IL-6, are produced by immune cells and play a significant role in driving inflammation and triggering oxidative stress

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Indeed, studies have documented increases in sex hormone-binding globulin (SHBG), luteinizing hormone (LH), and follicle-stimulating hormone (FSH) in men treated with GLP-1 RAs, suggesting a relief of metabolic inhibition on the pituitary-gonadal axis