Decreased FSH activity leads to reduced activation of G protein-coupled receptor (GPCR) and adenylyl cyclase (AC) signaling, resulting in insufficient cAMP production, which makes oocytes more susceptible to oxidative stress-induced apoptosis
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Stack the two gaps together and the picture for the conventional protocol is unflattering: approximately one-fifteenth of the studied dose, delivered by a route that animal data suggest requires several-fold more peptide, targeting a compound whose dose-response may not be monotonic anyway
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pastoris secreted recombinant DSIP-CBBBP on neurotransmitter levels, we quantified the concentrations of melatonin, serotonin, dopamine, and glutamate in the mouse serum