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Participants on semaglutide 2.4 mg lost a mean of 14.9% of baseline body weight over 68 weeks compared to 2.4% with placebo

New Scientist

Patients with connective tissue disorders, a history of bariatric surgery, or significant prior weight cycling may experience more pronounced laxity

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People transitioning from supplement-based GLP-1 support to injectable medications should work with a healthcare provider to determine appropriate starting doses and titration schedules rather than self-directing their protocol