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Phentermine is a sympathomimetic amine stimulant, not a GLP-1 receptor agonist

78 Senescence of tissues and organs lead to numerous age-associated degenerative disorders, including cancer, insulin resistance, obesity, metabolic syndrome, type II diabetes, inflammatory arthritis, atherosclerosis, and neurodegenerative disease

The landscape of metabolic health is evolving faster than ever

This class of drugs was first used to treat type 2 diabetes

Previous research had suggested some benefit for kidney transplant recipients with a history of type 2 diabetes who took the medications, originally designed to treat diabetes, at some point after their transplant and then experienced slower declines in kidney function than those who did not

Importantly, sarcopenia can hinder GLP-1mediated metabolic function in overweight and diabetic individuals, as skeletal muscle, responsible for ~7080% of insulin-stimulated glucose uptake, is the primary site of insulin-mediated glucose disposal