Davies, H
Pharmaceutical Research 32 , 30553065 (2015)
Conventional medications (antidepressants, anti-anxiety, anti-seizure, anti-psychotic, and narcotics) do not address the underlying causes that create the symptoms associated with TBI (PTS/PCS) because they do not replenish the missing neurosteroids (brain hormones)
Similar content being viewed by others Introduction Epigenetic regulation of gene expression refers to chromatin-based mechanisms that do not introduce changes in the DNA sequence per se and is not necessarily heritable
Abbreviations AMPK, AMP-activated protein kinase
Converging evidence highlights mitochondrial dysfunction and oxidative stress, resulting from excessive production of reactive oxygen species (ROS) and/or insufficient antioxidant defenses, in both peripheral tissues and brain samples of individuals with ASD ( In this biological context, natural compounds with antioxidant and anti-inflammatory properties have attracted growing interest as complementary strategies to modulate redox homeostasis, immune signaling, and mitochondrial function in ASD