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[43] [44] Gallbladder and biliary risk [edit] Semaglutide treatment is associated with an increased risk of biliary disease, specifically gallstones (cholelithiasis)

Anjana RM, Unnikrishnan R, Deepa M, Pradeepa R, Tandon N, Das AK, et al

Metabolic Health : Beyond weight loss, semaglutide has been found to improve metabolic health by aiding in the regulation of blood sugar levels, which is particularly beneficial for individuals with type 2 diabetes or prediabetes

Ensure physical safety : Sit or lie down in a safe place to prevent injury if you feel faint or dizzy

Tirzepatide does not yet have this cardiovascular indication

The drug's manufacturer has also provided some guidance to minimise the triggers for inflammation