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Also, B12 levels are not generally checked during routine blood work

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Diffusion-weighted imaging can distinguish acute lacunar infarction from chronic lesions

For research integrity, lyophilized material should be returned to frozen storage as soon as practical

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Treatment duration proves critical variable where longer courses create more durable changes - users completing 2-3 month treatments typically maintain 20-40% of peak benefits long-term, 4-6 month treatments sustain 40-60% of improvements, and 6-12+ month courses preserve 50-70% of maximum benefits potentially indefinitely