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In the VTA, GLP-1R activation via central administration of GLP-1RAs such as exendin-4 modulates neuronal excitability, in part by enhancing AMPA/kainate receptor activity on glutamatergic inputs and by regulating local GABAergic interneuron tone [10,23]

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Celebrating more than 80 years of service, it leads nationally in cancer care, cardiology, neurosciences, liver and kidney transplants and pediatrics, among other areas