10.1186/s12935-022-02496-z 178 WenJ.YiZ.ChenY.HuangJ.MaoX.ZhangL.et al (2022)
Effects of exenatide and liraglutide on heart rate, blood pressure and body weight: systematic review and meta-analysis
Not everyone can tolerate these medications certainly
No serious adverse events, hospitalization, organ damage, or deaths have been documented in over 100 preclinical studies, even at doses 1,000 times higher than typical therapeutic use
What the pharmacokinetic data shows Eli Lilly's injection site study measured how much tirzepatide reached the bloodstream (total exposure, or AUC) and the peak concentration (Cmax) after a 5mg subcutaneous injection in the abdomen, thigh, and upper arm
Only remove doses from refrigeration when actively preparing an injection, and return unused medication immediately to maintain stability