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recommended daily allowance (RDA) is: 2.4 micrograms (mcg) per day Certain groups may require higher intake, including: Pregnant women: 2.6 mcg daily Breastfeeding women: 2.8 mcg daily Older adults Vegetarians and vegans Individuals with absorption issues 500 mcg to 5000 mcg , which is significantly higher than the RDA but still generally considered safe when medically supervised

Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes

Intermediate feedback occurs within 4 hours time frame and involves inhibition of CRH synthesis and release from CRH neurons, not affecting ACTH synthesis (209)

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Research is ongoing and the peptide doesnt have FDA approval