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The current study comprised a screening visit (up to 3 weeks before randomization), a DPP4 inhibitor washout period, three treatment periods, and a follow-up visit (Fig

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doi:10.1016/j.mayocp.2018.10.014 Jensen MD, Ryan DH, Apovian CM, et al

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In-Vitro Pharmacology and Selectivity Biochemical profiling places 5-Amino-1MQ potency for research NNMT in the low-micromolar IC range under standardized assay conditions, with cell-based EC values in the low micromolar range for lowering 1-MNA and suppressing lipogenesis

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