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Forty percent of the children were exposed to acetaminophen in utero

These can still be part of the overall approach, but I see them as symptom management strategies, rather than root cause medicine

10.1126/science.290.5497.1721 122 SingerS.NicolsonG

This lead us to investigate whether TNF- as a classical proinflammatory cytokine and TGF- as central profibrotic stimulus regulated GPX3 expression in primary human bronchial epithelial cells and fibroblasts

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Activated immune cells produce pro-inflammatory cytokines, such as Interleukin-1beta (IL-1), Tumor necrosis factor alpha (TNF-), and Interleukin-6 (IL-6), which are highly expressed in the synovium and promote inflammatory responses leading to cartilage degradation