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In fact, its thought that as many as 90% of the people who follow these diets are deficient in vitamin B-12 because one of the only natural sources for B-12 is in animal food products

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This matters for safety and efficacy

Generally: A normal level of vitamin B12 in your bloodstream is 160-950 picograms per milliliter (pg/mL)

Less commonly, vitamin B12 deficiency results from an inadequate intake of foods that contain vitamin B12