Zhiqi Hu provided many suggestions during study design and manuscript preparation
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1 Side effects from creatine most commonly center around a mild GI upset at higher doses or when mixed into a small volume of water
[1] [2] GLP-1 medications work through several complementary mechanisms: Enhancing insulin secretion : They stimulate the pancreas to release insulin when blood glucose levels are elevated, helping to lower blood sugar in a glucose-dependent manner Suppressing glucagon release : They reduce the secretion of glucagon, a hormone that raises blood glucose, thereby preventing excessive glucose production by the liver Slowing gastric emptying : They delay the rate at which food leaves the stomach, leading to more gradual glucose absorption and increased feelings of fullness Reducing appetite : They act on areas of the brain involved in appetite regulation, helping to decrease food intake [2] [22] Commonly prescribed GLP-1 receptor agonists in the UK include semaglutide (Ozempic for diabetes, Wegovy for weight management, Rybelsus as an oral formulation), dulaglutide (Trulicity), liraglutide (Victoza for diabetes, Saxenda for weight management), and exenatide (Byetta, Bydureon)
Its primary physiological role is to regulate how the body stores, utilizes, and distributes glucose, fats, and proteins in the post-prandial state
doi:10.1097/00006676-200110000-00012 140
