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SGLT2 inhibition and adipose tissue metabolism: current outlook and perspectives
Semaglutide can be prescribed, monitored, and adjusted within a clinical setting today
Moreover, short-term experiments may not be able to detect the impact of ANG II suppression on aldosterone levels, since aldosterone has slower rates of secretion and degradation than ANG II (66)
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Sound mechanistic evidence supports the need for further research on the GLP1-RAs/SGLT2is combinations ability to modify specific risk outcomes, such as cardiovascular risk and the progression of diabetic kidney disease
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