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Influenced by genetics and strongly linked to heart disease and blood clotting problems, this risk factor unfortunately is not part of routine cholesterol tests or standard lipid panels

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Cortisol affects neuronal mitochondrial function in a biphasic manner : Low, normal levels of cortisol increase mitochondrial function Chronically high levels of cortisol decrease mitochondrial function.[ref] Chronic stress alters cortisol levels and thus can affect mitochondrial function in the brain