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Norleucine-YIHPF (Nle'-Ang-iV), D-Nle-YI, Acetyl-NleYIH, Gamma Amino Butyric Acid- YIH, NleYI-amide, N-hexanoic-YI-(6) aminohexanoic amide (dihexa) were synthesized by Fmoc based solid phase methods in the Harding laboratory

In this review, both existing and emerging targets, including the proteins, small molecular metabolites, and epigenetic regulators related to RA, are discussed, with a focus on the mechanisms that result in inflammation and the development of new drugs for blocking the various modulators in RA

doi: 10.3389/fcell.2025.1619758 Received 28 April 2025 Accepted 13 June 2025 Published 26 June 2025 Volume 13 - 2025 Edited by Marcela Alejandra Michaut, CONICET Dr

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