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Hypothalamicpituitaryadrenal axis, neuroendocrine factors and stress

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It is most effective when taken with meals containing carbohydrates or before workouts to enhance energy and fat metabolism

Sip water frequently rather than consuming large volumes at once, which can trigger nausea when combined with tirzepatide's slowed gastric emptying

Think vegetables, whole grains, wheat bran, and nuts

The study met both coprimary endpoints showing greater improvement with tirzepatide in both percentage of weight loss and number of participants achieving at least 5% weight loss compared to placebo [39]