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Contaminated injections pose a greater infection risk for individuals whose immune systems are already dysfunctional or suppressed by medication

The short half-life of the active peptide in the body is separate from solution stability, but degradation in the vial is still a concern

Clinicians should monitor for gallbladder disease, pancreatitis symptoms, dehydration-related acute kidney injury, heart rate increase, diabetic retinopathy worsening in patients with diabetes and rapid glycemic improvement, and dysesthesia-associated adverse events at higher doses

With time, disc bulges or herniations, malalignment of the vertebral segments (spondylolisthesis), osteophyte (bone spur) formation, enlargement (hypertrophy) of facet joints, and ligamentum flavum thickening may all gradually contribute to a narrowing of the spinal canal

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