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They exist in a regulatory gray area, often sold with labels that say "for research purposes only." This matters for a few reasons: Quality control is inconsistent

Two of the most commonly referenced forms are: GHK-Cu (Copper Tripeptide-1) AHK-Cu (Copper Tripeptide-3) While both belong to the copper peptide family, they are used differently in cosmetic formulation depending on whether the goal is skin-focused or scalp- and hair-focused performance

Paul KC, Zhang K, Walker DI, Sinsheimer J, Yu Y, Kusters C, et al

Some patients feel wired, anxious, or irritable if they start with a high dose of methyl-folate

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Is leaky gut a real medical condition