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Nat Commun 9: 1062, 2018

In certain embodiments, the increase in exposure of an active agent and the increase in the length of time that the concentration of the active agent is above C min by a controlled-release otic formulation described herein is greater than 100% compared to a formulation that is not a controlled-release otic formulation

18: Bains JS, Shaw CA (1997)

287 The currently developed JHU-083 is a prodrug of 6-Diazo-5-oxo-L-norLeu (L-DON) generation glutaminase inhibitor that selectively activates L-DON in the TME

Nebulized inhalation of LPAE-HDAC10 inhibits acetylation-mediated ROS/NF-B pathway for silicosis treatment

Visit a walk-in clinic or see your family doctor to rule out underlying medical conditions