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Compound 20 inhibited the production of pro-inflammatory factors such as TNF-, COX-2, and IL-6 in LPS-stimulated murine RAW264.7 macrophages
In most instances of RTK trafficking to the nucleus, an intracellular domain (ICD) fragment of the receptor is generated through proteolytic processing and the ICD then enters the nucleus [108]
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Huang J, Zhang Z, Guo J, Ni A, Deb A, Zhang L, et al
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PubMed Randomized trialSemaglutide evidence2021 Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance Used for maintenance, discontinuation, and weight-regain discussions after semaglutide response
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