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Indeed, the mitochondrial inner membrane is impermeable to fatty acyl-CoAs and a specialized system, well known as carnitine shuttle, is needed for translocating fatty acids moieties, conjugated with carnitine, into mitochondrial matrix for the -oxidation

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They also measured glutamate levels in the basal ganglia using magnetic resonance spectroscopy (MRS) and myo-inositol, a marker for glial health

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