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(2) Emulsion-evaporation method in which PLGA and agents to be encapsulated are dissolved in a volatile water-immiscible organic solvent, which is emulsified into aqueous external phase followed by evaporation of the organic solvent to form PLGA nanoparticles

doi: 10.1038/s41588-018-0248-z 73 SullivanPFEvengrdBJacksAPedersenNL

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Immune Component Impact on BBB Integrity In inflammatory states, endothelial cell expression of TJs proteins decreases and adhesion molecule expression increases (De Laere et al., 2020) or by serum from patients with breast cancer and brain metastasis tested on CD34 + -derived endothelial cells (Curtaz et al., 2020)

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