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Ans : Slightly, with long-term use

The company was afraid that physicians wouldnt be able to differentiate between the risk of DKA in type 1 diabetes being 2-4% in a year, or in people with type 2 diabetes, where the risk is very, very low, Mathieu said

People on certain medications including diuretics, beta-blockers, tricyclic antidepressants, and aspirin have heightened susceptibility

Food, coffee, juice, or other medications taken too soon can interfere with absorption and reduce how well the medication works, or stop it working altogether

Factor 2: Dosage and Unflinching Consistency This seems obvious, but it's a common point of failure

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