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Medical Context: Obesity is recognized by major medical organizations including the American Medical Association, American College of Cardiology, and The Obesity Society as a chronic disease requiring long-term medical management, similar to hypertension, diabetes, or hyperlipidemia

Semaglutide is FDA approved to treat type 2 diabetes under the brand names Ozempic and Rybelsus

With respect to ALT, there was a mean reduction that reached the threshold of statistical significance (mean deviation [MD] = 10.84

Synthetic semaglutide API is manufactured using solid-phase peptide synthesis (SPPS) technology with Fmoc chemistry, building the 31-amino acid peptide chain sequentially on a resin support before cleaving, purifying, and attaching the fatty acid side chain

Increasing heart rate Worsening depression, behavior changes, or suicidality Note: Never share the Mounjaro pen with other people SIDE EFFECTS INFORMATION Many people experience no side effects

6 , CD007938 (2017)