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Because B12 is water-soluble and excess is excreted through urine, mega-dosing B12 is generally considered safe

[1] [3] These areas have altered tissue architecture that may predispose to reactions

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Strict, unforgiving schedules often lead to higher dropout rates, whereas protocols that allow for minor lapses tend to support better long-term compliance

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Effects of the twin-arginine translocase on secretion of virulence factors, stress response, and pathogenesis