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Combination Research Considerations The mechanistic non-overlap between Epitalon and GHK-Cu suggests potential research value in combination protocols: Upstream + downstream senescence targeting: Epitalon addresses telomere shortening (the upstream trigger of replicative senescence) while GHK-Cu suppresses SASP (the downstream consequence of established senescence) Circadian + antioxidant coverage: Epitalon restores melatonin circadian amplitude

Cortisol-induced insulin resistance in man: impaired suppression of glucose production and stimulation of glucose utilization due to a postreceptor defect of insulin action

Li RJ, Liu Y, Liu HQ, Li J

The difficulty is that this damage is not always visible

It may also lower levels of a chemical called homocysteine, which has links to heart attack and stroke

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