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Histamine acts as a chemical messenger and is involved in numerous physical processes from gastric acid secretion to muscle contraction, however its levels in the body are usually very tightly regulated(2,4)

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Psychological evaluation

Its not unique to Ozempicsimilar effects occur with any form of rapid weight loss, including bariatric surgery or crash diets

The increased diversity of the gut microbiota significantly correlates with the sparing of the hypothalamic microstructure in obese and non-obese individuals [44] Furthermore, in animal models, the gut microbiota modulates hypothalamic gene expression, neuropeptide secretion, neurotransmitter levels, and neuronal activity [45, 46]