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Recombinant oligomeric A 40 preparations contained large amounts of low molecular weight species corresponding to monomer, dimer, trimer and tetramer, with a smear of A species between 16 kDa and 50 kDa

Cluster analysis (Figure S5B) demonstrated clear separation between groups: controls clustered with high Bacteroidota/Actinomycetota representation, ASD models formed a distinct Firmicutes-dominated cluster, and hCiPSCs-treated animals occupied an intermediate position

The research team also recorded the frequency of adverse events and serious adverse events in both the primary study and the extended study [3]

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