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Group II (10 patients) received oral glutathione capsules (500mg/day) for 4 weeks

Insulin, IGF-1 and cancer Molecular pathways Insulin and the IGFs, IGF-1 and IGF-2, are structurally similar peptides with important roles in controlling metabolism and growth in response to nutrient signals and nutritional status

doi: 10.1073/pnas.0510033103 36 RommelCBodineSCClarkeBARossmanRNunezLStittTNet al

To maintain the balance of ROS, the antioxidant system within organisms comprises endogenous enzymes (such as GPX and TrxR) and exogenous antioxidants (such as Vitamin E)

This means higher IGF-1 levels increase risk for certain cancers and make some more difficult to treat

It is a prescription drug for its approved use