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Murine RAW264.7 macrophages were induced with LPS following pre-treatment with Ginsenoside Rh1 at 5, 10, 25, and 50 M, and confirmed that at as low as 5 M, TNF-, IL-1, MCP-1, iNOS, and COX2 mRNA expression were reduced

The team combined insights from genetics and molecular design to engineer a molecule that could both block the GIP receptor and activate the GLP-1 pathway

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Mouse grouping before the start of the experiments and mouse picking for data collection at the end were determined with an online random number generator ( Sample size estimation mainly depends on statistics