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In approved medicines, clomiphene is a mixture of two isomers: cis (Z-isomer or zuclomiphene) and trans (E-isomer or enclomiphene)

Purine nucleoside phosphorylase (PNP) is significantly increased in IBS-C and IBS-D patients, however, it is negatively correlated with hypoxanthine concentration (Mars et al., 2020)

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What To Expect Duration Typically ranges from 30-60 minutes Expect Results On average, a series of 6 to 10 sessions spaced at regular intervals, such as weekly or bi-weekly, is often recommended to achieve optimal results

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Study 3: IV safety (2025)