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Combination therapy has several potential advantages, including (1) increased durability of the glycaemic effect [225227], addressing therapeutic inertia, (2) simultaneous targeting of the multiple pathophysiological processes characterised by type 2 diabetes, (3) impacts on medication burden, medication-taking behaviour and treatment persistence and (4) complementary clinical benefits (e.g

This potential is worth taking seriously precisely because cravings are so central to relapse

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Previous studies have shown that activation of the glucagon-like peptide-1 receptor (GLP-1R) leads to anti-inflammatory and anti-apoptotic effects

Nutritional consequences of interspecies differences in arginine and lysine metabolism