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Retatrutide is an investigational once-weekly injectable peptide that simultaneously activates GLP-1, GIP, and glucagon receptors, distinguishing it from approved single or dual receptor agonists such as semaglutide and tirzepatide

PP-TR-US-0839 03/2023 Lilly USA, LLC 2023

08) Appetite Suppressants / Weight Loss Medicines Interaction: May enhance weight loss effects when combined with SEMALIX 14 TABLET

Structure, function, and regulation of the blood-brain barrier tight junction in central nervous system disorders

Local injection site reactions were uncommon in the Phase 2 trial, occurring at a lower frequency than systemic gastrointestinal events

Tornio A, Filppula AM, Kailari O, Neuvonen M, Nyrnen TH, Tapaninen T, et al