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Old, damaged tissue accumulates while new tissue production declines

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Lactobacillus casei reduces susceptibility to type 2 diabetes via microbiota-mediated body chloride ion influx

There are three main types of melanin: The combination and concentration of these types determine the variations in human pigmentation

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In the liver, S1PR2 activates pro-insulin signaling through enhancing insulin-degrading enzyme (IDE), thereby potentially alleviating insulin resistance associated with T2DM and AD based on animal mechanistic studies (Vettorazzi et al., 2017