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They differ sharply in evidence quality

FDA-approved Crohn's treatments include biologic therapies (infliximab, adalimumab, vedolizumab, ustekinumab, risankizumab), JAK inhibitors (upadacitinib), corticosteroids for induction (budesonide, prednisone), and immunomodulators (azathioprine, methotrexate)

The species are based on serogroups A-J and putative species RVK and RVL are already reported [45]

GHK-Cu supports recovery by activating repair-related genes, regulating inflammation, promoting collagen and elastin production, and improving blood vessel formation