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Regarding the redox-dependent structural changes in the recombinant GSAAT proteins, the mobility of the GSAAT(C138S) mutant was found to be similar to the wild type under various conditions, suggesting that a role of Cys138 in the formation of redox-dependent intra- and intermolecular disulfide bridges can be excluded (data not shown)

The aberrant expression of GSH-degrading enzymes is associated with the prognosis of certain cancers such as gastric adenocarcinoma (72), breast cancer (74) and so on, making them promising tumor biomarkers

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suggested that platelet-activating factor was responsible for TLR-4 over-expression 20

This decline is linked to cell damage, inflammation, and accelerated aging both internally and externally

Under hyperglycemic conditions, we observed a significant decrease in the percentage of SC- cells and an increase in the percentage of SC- cells in pure SC- cell aggregates (Fig