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All except one of the six genetic studies considered Hardy Weinberg equilibrium [47, 50, 94, 96, 97], two provided power calculations [96, 97] and two adjusted for multiple comparisons [50, 97] (although a footnote indicating that the associations were no longer statistically significant was not added in one case) [50]

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GLP-1 RAs also improve insulin sensitivity, reduce ectopic fat deposition, and modulate adipose tissue metabolism by stimulating lipolysis and inhibiting lipogenesis [12, 13]

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