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These medications remain licensed exclusively for type 2 diabetes mellitus and obesity

Viera Kupov has no conflicts of interest to report

When semaglutide is prescribed for weight management, coverage becomes much less predictableeven though Wegovy is FDA-approved for that purpose

As described in the European Medicines Agency's European Public Assessment Report (EPAR), it works by enhancing insulin secretion in a glucose-dependent manner, suppressing glucagon release, slowing gastric emptying, and reducing appetite through central nervous system pathways