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Over-the-counter remedies that may help If lifestyle changes aren't enough, there are safe over-the-counter options to consider: Osmotic laxatives like polyethylene glycol (Miralax) draw water into the bowel to soften stool Magnesium citrate works similarly and is often recommended by experts for GLP-1-related constipation Stool softeners like docusate sodium can make stools easier to pass without stimulating the intestines Fiber supplements can help, but start with a low dose and increase gradually while drinking plenty of water Talk to your doctor or dietitian before trying any supplements

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In Histopathology of Preclinical Toxicity Studies

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