what's better semaglutide or tirzepatide for weight loss vs Semaglutide vs Tirzepatide Compound: Key

Higdon A, Diers AR, Oh JY, Landar A, Darley Usmar VM (2012) Cell signalling by reactive lipid species: new concepts and molecular mechanisms

Abbreviations GLP-1RA: Glucagon-like peptide-1 receptor agonist(s) IPTW: Inverse probability of treatment weighting SGLT-2i: Sodium-glucose cotransporter 2 inhibitor(s) SIS: Suicidal ideation and self-injury VHS: Valencia Health System VID: Valencia Health System Integrated Database References Davies MJ, Aroda VR, Collins BS et al (2022) Management of hyperglycemia in type 2 diabetes, a consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

& Wang, F

The development of oral semaglutide, an oral GLP-1 analog, for the treatment of type 2 diabetes

Is the safety profile stable at scale

Importantly, semaglutide carries a boxed warning regarding the risk of thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)