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Microdosing means taking a lower-than-standard dose of a GLP-1 medication to activate its broader health effects while minimizing side effects like nausea or fatigue

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Activation, mtDNA, particularly in its oxidized form (ox-mtDNA), can also directly activate the NLRP3 inflammasome, promoting caspase-1 activation, maturation of IL-1 and IL-18, and GSDMD (Gasdermin D)-mediated pyroptosis, thereby fueling chronic inflammation (77, 78)