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Of note, APOE4 exacerbates mitochondrial dysfunction and oxidative stress within neurons, thereby amplifying neurotoxicity and contributing to neurodegenerative processes (Chen et al., 2021)

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Like vestibular neuritis, labyrinthitis can be caused by an infection and leads to vertigo along with hearing loss

All patients received a standard lifestyle intervention which included instruction on a reduced-calorie diet (approximately 500 kcal/day deficit) and increased physical activity counseling (recommended minimum of 150 min/week) that began with the first dose of ZEPBOUND, during the lead-in period, and continued throughout the trial

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