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DRUG INTERACTIONS As with other medications, zonisamide can interact with certain medications, including carbonic anhydrase inhibitors (such as acetazolamide), orlistat (if using zonisamide for a seizure disorder), phenobarbital, primidone, rifamycins, glucocorticoids, and St

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And even a few hours of heat exposure can compromise your medication

However, supplementation is necessary during disease states, especially in inflammatory bowel diseases and leaky gut (autoimmune diseases can indicate this!), before and after surgery, in trauma or mental illness and for very physically active people

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